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Interlocking Pieces

Signaling pathways are often thought of as linear events.

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Network Evolution

In the early days of systems biology, the focus was primarily on assembling parts lists and in understanding how those parts – the genes and the proteins they encode – were assembled into networks.

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Systems Under Stress

Single-celled Halobacterium salinarum specializes in stress.

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Evil Twin

The genetic circuits that keep us to a roughly 24-hour circadian clock are no doubt complex.

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An Alternate Fate

When embryonic sea urchins have just 16 cells, four of them are destined to produce the skeleton.

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Take Pause

If you starve a nematode worm, it will live as if in suspended animation.

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Director’s Message March 2011

A Whole New World.

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It’s the Network

In Genomic Age, Systems Biology Approach Takes Root in the Search for Fundamental Insights.

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On the Move

Scientists are Realizing Just How Influential MicroRNA Can Be.

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It’s a Small World

As MicroRNA List Grows, So Does Genomic Complexity.

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